Peptide Database

Peptide NameNisin A

Function Ontology

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Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC132H233N35O42S6

DescriptionStandard

        ITSKSLCTPGCVTGVLMGCALKTITCNCSVGI
    

Molecular Weight3174.86 Da

Isoelectric Point (pI)8.43

Net Charge (pH 7.0)1.71

Net Charge (pH 7.4) 1.43

Charge Density (pH 7.0) 0.0534

GRAVY Index1.04

Hydrophobic Moment 0.36

Boman Index0.34

Instability Index3.35

Aliphatic Index 103.44

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1213.60

LogP -15.86

H-bond Donors 48.0

H-bond Acceptors 50.0

Rotatable Bonds 103.0

Heavy Atoms 215.0

Ring Count 1.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0090148 VERIFIED: YES

Provenance & Taxonomy

OrganismEnterococcus rotai [Bacterium]

FamilyBacteriocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)