Peptide Database

Peptide NameSLAY-screened peptide P2206

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC90H139N27O38S3

DescriptionStandard

        RSEDCDRSTSCNFTCTSYDL
    

Molecular Weight2303.42 Da

Isoelectric Point (pI)4.23

Net Charge (pH 7.0)-2.26

Net Charge (pH 7.4) -2.52

Charge Density (pH 7.0) -0.1132

GRAVY Index-0.95

Hydrophobic Moment 0.32

Boman Index-0.34

Instability Index115.48

Aliphatic Index 19.50

Aromaticity 0.1000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1094.15

LogP -17.56

H-bond Donors 43.0

H-bond Acceptors 39.0

Rotatable Bonds 74.0

Heavy Atoms 158.0

Ring Count 2.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0288508 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/