Peptide Database

Peptide NameC-terminal-flanking peptide

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Tachykinin peptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC123H189N37O41

DescriptionStandard

        GKRSQEEPESYEWGTVQIYDKRR
    

Molecular Weight2842.04 Da

Isoelectric Point (pI)6.31

Net Charge (pH 7.0)-0.23

Net Charge (pH 7.4) -0.45

Charge Density (pH 7.0) -0.0101

GRAVY Index-1.97

Hydrophobic Moment 0.36

Boman Index-0.51

Instability Index122.05

Aliphatic Index 29.57

Aromaticity 0.1304

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1322.09

LogP -13.97

H-bond Donors 47.0

H-bond Acceptors 41.0

Rotatable Bonds 96.0

Heavy Atoms 201.0

Ring Count 5.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0012089 VERIFIED: NO

Provenance & Taxonomy

OrganismCarassius auratus [Animal]

FamilyC-terminal-flanking peptide

Tax ID7957

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Neuromodulator Vasoactive Vasodilator Receptor modulation

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0406791 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0409497 VERIFIED: NO

Provenance & Taxonomy

OrganismCarassius auratus [Animal]

FamilyTachykinin

Tax ID7957

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Tachykinin Neuropeptide Neuromodulator