Peptide Database

Peptide NameDisintegrin Echistatin alpha1

Function Ontology

Hemostasis ▸ Antithrombotic activity

Standard StatusStandard

Sequence Length49 amino acids

Chemical FormulaC217H349N71O74S9

DescriptionStandard

        ECESGPCCRNCKFLKEGTICKRARGDDMDDYCNGKTCDCPRNPHKGPAT
    

Molecular Weight5425.11 Da

Isoelectric Point (pI)7.77

Net Charge (pH 7.0)0.85

Net Charge (pH 7.4) 0.50

Charge Density (pH 7.0) 0.0173

GRAVY Index-1.13

Hydrophobic Moment 0.48

Boman Index-0.34

Instability Index35.02

Aliphatic Index 20.00

Aromaticity 0.0408

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2360.16

LogP -32.24

H-bond Donors 88.0

H-bond Acceptors 85.0

Rotatable Bonds 179.0

Heavy Atoms 371.0

Ring Count 7.0

Amide Bonds 51.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0370929 VERIFIED: NO

Provenance & Taxonomy

OrganismEchis carinatus [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-11; 7-32; 8-37; 20-39

Bio-Activity Profile

Function

Aggregation Regulator

RECORD: Rec_0420875 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antithrombotic