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MYP_050392
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Basic Information
Cyclic [W
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
9 amino acids
C79H100N26O10
Standard
Sequence
WRWRWRWRW
Physicochemical Analysis
1573.81 Da
12.00
3.76
3.56
0.4178
-2.50
0.12
-0.67
263.47
0.00
0.5556
27500.00
27500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
622.67
0.95
27.0
14.0
43.0
115.0
10.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0281951 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Doxorubicin (Dox) is a well-known anthracycline which has been conjugated to a CPP
32630
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Doxorubicin (Dox) which is anthracycline attached with linker to CPP [W(RW)4 ]
Bio-Activity Profile
Anticancer Cytotoxic
SK-OV-3
1 μM
Inhibition
PMID23301519 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23301519/
RECORD: Rec_0318970 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Doxorubicin (Dox) which is anthracycline attached with linker to CPP [W(RW)4 ]
Bio-Activity Profile
Anticancer
PaperCancerPPD: a database of anticancer peptides and proteins PMID25270878 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25270878/
RECORD: Rec_0358984 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
Dox, Doxorubicin
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID23301519 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23301519/
RECORD: Rec_0423750 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
Dox, Doxorubicin
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID23301519 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23301519/
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