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MYP_050391
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Basic Information
FluA-PB1(1-8)
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Standard
8 amino acids
C39H67N9O13S
Standard
Sequence
MDVNPTLL
Physicochemical Analysis
902.07 Da
4.05
-1.50
-1.71
-0.1873
0.55
0.23
0.28
5.15
133.75
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
358.85
-2.47
11.0
13.0
27.0
62.0
1.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0163483 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Influenza A(FluA):inhibition of PA-binding activity and virus replication
3 μM
IC50
PaperPubMed PMID: 19841738 PMID19841738 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19841738/
RECORD: Rec_0221267 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0229176 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Replication inhibition
Influenza A (FluA)
3 μM
IC50
Mammalian: 30 h; Yeast: >20 h; E. coli: >10 h
PaperIdentification of a PA-binding peptide with inhibitory activity against influenza A and B virus replication. | Wunderlich K, Mayer D, Ranadheera C, Holler AS, Mänz B, Martin A, Chase G, Tegge W, Frank R, Kessler U, Schwemmle M. | PLoS One. 2009 Oct 20;4(10):e7517. | DOI:10.1371/journal.pone.0007517 | PMID:19841738 PMID19841738 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19841738/
RECORD: Rec_0294498 VERIFIED: YES
Provenance & Taxonomy
Influenza A virus [Virus]
Virus-derived peptide
11320;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Replication inhibitor
Influenza A virus (Replication); MDCK
3 μM
ELISA
PaperIdentification of a PA-binding peptide with inhibitory activity against influenza A and B virus replication. | Wunderlich K, Mayer D, Ranadheera C, Holler AS, Manz B, Martin A, Chase G, Tegge W, Frank R, Kessler U, Schwemmle M. | PLoS One. 2009 | PMID:19841738 PMID19841738 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19841738/
RECORD: Rec_0300872 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 19841738 PMID19841738 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19841738/