Peptide Database

Peptide NameDefensin-1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length115 amino acids

Chemical FormulaC590H927N155O161S9

DescriptionStandard

        MVKIYFLVALLFVAVAATVAVPVVLATFELMITRLWTFKYLLDNLEEYEPFELHGVEERADRQRRVTCDLLSGFVEHSACAANCLSMGKAGGRCENGICICRKTTFKELWDKRFG
    

Molecular Weight13056.20 Da

Isoelectric Point (pI)6.71

Net Charge (pH 7.0)-0.36

Net Charge (pH 7.4) -0.80

Charge Density (pH 7.0) -0.0031

GRAVY Index0.28

Hydrophobic Moment 0.56

Boman Index0.11

Instability Index34.33

Aliphatic Index 98.35

Aromaticity 0.1130

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5060.95

LogP -36.67

H-bond Donors 185.0

H-bond Acceptors 172.0

Rotatable Bonds 432.0

Heavy Atoms 915.0

Ring Count 19.0

Amide Bonds 118.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0138003 VERIFIED: NO

Provenance & Taxonomy

OrganismMelipona quadrifasciata [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal