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MYP_050330
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Basic Information
Margaratain-A1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Enzyme modulation ▸ Enzyme inhibition ▸ Inhibition of TNF-alpha production
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Standard
10 amino acids
C45H67N13O15S2
Standard
Sequence
FFSTSCRSGC
Physicochemical Analysis
1094.22 Da
8.07
0.74
0.51
0.0740
0.26
0.44
0.03
85.54
0.00
0.2000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
468.04
-7.64
20.0
18.0
33.0
75.0
2.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0035048 VERIFIED: NO
Provenance & Taxonomy
Odorrana margaratae [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0179812 VERIFIED: YES
Provenance & Taxonomy
Odorrana andersonii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans ATCC 2002
200 μg/mL
MIC
PMID22029824 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22029824/
RECORD: Rec_0246227 VERIFIED: YES
Provenance & Taxonomy
Odorrana andersonii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
200 μg/mL
MIC
PMID22029824 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22029824/
RECORD: Rec_0253859 VERIFIED: YES
Provenance & Taxonomy
Odorrana margaretae [Animal]
Margaratain
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
6-10
Bio-Activity Profile
Antioxidant Inhibition of TNF-alpha production Stimulation of IL-8 production
PaperX. Yang et al. / Journal of Proteome Research 11 (2012) 306-319. Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs PMID22029824 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22029824/
RECORD: Rec_0303562 VERIFIED: YES
Provenance & Taxonomy
Odorrana andersonii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Bacillus pyocyaneus CMCCB 10104
200 μg/mL
MIC
PMID22029824 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22029824/
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