MYP_050312
MyD88 inhibitor
Neuroprotective
Standard
24 amino acids
C140H227N45O33S
Standard
DRQIKIWFQNRRMKWKKRDVLPGT
3100.65 Da
11.58
5.76
5.55
0.2399
-1.41
0.42
-0.48
49.33
60.83
0.1250
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1331.19
-9.77
48.0
40.0
107.0
219.0
6.0
26.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0045522
VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Polypeptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuroprotective
HeLa cells (In vitro)
Cell viability assay; Cytotoxicity assay; ELISA; Western blot; Immunostaining; ROS assay
RECORD: Rec_0220569
VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Polypeptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuroprotective
Primary mouse RPE cells (In vitro)
Cell viability assay; Cytotoxicity assay; ELISA; Western blot; Immunostaining; ROS assay
RECORD: Rec_0297378
VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Polypeptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuroprotective
THP-1 cells (In vitro)
Cell viability assay; Cytotoxicity assay; ELISA; Western blot; Immunostaining; ROS assay
RECORD: Rec_0337945
VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Polypeptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuroprotective
Donor eyes or ocular tissues from patients with geographic atrophy due to AMD or age-matched patients without AMD (Ex vivo)
Cell viability assay; Cytotoxicity assay; ELISA; Western blot; Immunostaining; ROS assay
RECORD: Rec_0367764
VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Polypeptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuroprotective
Wild-type C57BL/6J mice (In vivo)
Cell viability assay; Cytotoxicity assay; ELISA; Western blot; Immunostaining; ROS assay