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MYP_050307
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Basic Information
Brevinin-1PRc
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
24 amino acids
C122H206N30O26S3
Standard
Sequence
FFPMLAGVAARVVPKVICLITKKC
Physicochemical Analysis
2605.32 Da
9.85
3.74
3.50
0.1557
1.28
0.67
0.35
26.98
125.83
0.0833
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
875.23
-2.81
32.0
33.0
83.0
181.0
4.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0254380 VERIFIED: YES
Provenance & Taxonomy
Rana pretiosa [Animal]
Brevinin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
18-24
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
12.5 μM
MIC
PaperJ.M. Conlon et al. / Developmental and Comparative Immunology 35 (2011) 644-649. Host defense peptides in skin secretions of the Oregon spotted frog Rana pretiosa: implications for species resistance to chytridiomycosis PMID21295070 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21295070/
RECORD: Rec_0374686 VERIFIED: YES
Provenance & Taxonomy
Rana pretiosa [Animal]
Brevinin
Structure & Mods
side-chain cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
18-24
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
PaperPubMed PMID: 21295070 PMID21295070 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21295070/
RECORD: Rec_0375487 VERIFIED: YES
Provenance & Taxonomy
Rana pretiosa [Animal]
Brevinin
69834
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
12.5 μM
MIC
PaperHost defense peptides in skin secretions of the Oregon spotted frog Ranapretiosa: implications for species resistance to chytridiomycosis
RECORD: Rec_0395926 VERIFIED: YES
Provenance & Taxonomy
Rana pretiosa [Animal]
Brevinin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25726
50 μM
MIC
PMID21295070 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21295070/
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