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MYP_050281
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Basic Information
AlbuBNP
Binding / Molecular interaction ▸ Binding activity
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Cardiac fibrosis Inhibitor
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic
Standard
32 amino acids
C143H246N50O42S4
Standard
Sequence
SPKMVQGSGCFGRKMDRISSSSGLGCKVLRRH
Physicochemical Analysis
3466.05 Da
10.95
5.53
5.23
0.1727
-0.51
0.71
-0.21
86.78
54.69
0.0312
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1512.74
-20.75
58.0
53.0
121.0
239.0
3.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0324682 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Natriuretic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Vasodilator
Radioimmunoassay
Human blood plasma, in vitro; 726 s
PMID17479256 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17479256/
RECORD: Rec_0346721 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0354280 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Brain natriuretic peptide
9606
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
10-26
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation ACE inhibitory
Experimental: 3.1 minutes; /186 seconds; Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Brain natriuretic peptide 32 (Homo sapiens): PMID 11054637 PMID11054637 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11054637/
RECORD: Rec_0362623 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/
RECORD: Rec_0375783 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
10-26
Bio-Activity Profile
Neuropeptide
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