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MYP_050281
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Basic Information
AlbuBNP
Binding / Molecular interaction ▸ Binding activity
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Cardiac fibrosis Inhibitor
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic
Standard
32 amino acids
C143H246N50O42S4
Standard
Sequence
SPKMVQGSGCFGRKMDRISSSSGLGCKVLRRH
Physicochemical Analysis
3466.05 Da
10.95
5.53
5.23
0.1727
-0.51
0.71
-0.21
86.78
54.69
0.0312
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1512.74
-20.75
58.0
53.0
121.0
239.0
3.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0209366 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Natriuretic peptide
9606
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
10月26日
Bio-Activity Profile
Natriuretic Vasodilator Cardiovascular
Natriuretic peptide receptor A
Clinical/Human: 18 min
Evidence URLhttps://www.accessdata.fda.gov/drugsatfda_docs/label/2006/020920s012lbl.pdf
RECORD: Rec_0225679 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Natriuretic peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Vasodilator
ELISA
Human plasma, in vitro; ~1320 s
PMID18553094 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18553094/
RECORD: Rec_0231036 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Natriuretic peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Vasodilator
Human plasma of patients with mild, stable heart failure, in vivo; 336 s
PMID16476851 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16476851/
RECORD: Rec_0269808 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Natriuretic peptide
9606
Structure & Mods
linear peptide/protein therapeutic [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Cardiovascular Vasodilator Natriuretic
Approx. 18 min
PaperPubMed-linked source references: PMID:17826644; PMID:12668889; PMID:12549957; PMID:12070532; PMID:12028606 PMID17826644;12668889;12549957;12070532;12028606 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17826644/
RECORD: Rec_0303101 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
natriuretic peptide family
9606; 0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
10-26
Bio-Activity Profile
Hormone natriuretic peptide family Angiogenic
PaperPDB 3N56 structural record; X-ray; 3.10 A; chain C/D; residues 1-32
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