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MYP_050281
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Basic Information
AlbuBNP
Binding / Molecular interaction ▸ Binding activity
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Cardiac fibrosis Inhibitor
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic
Standard
32 amino acids
C143H246N50O42S4
Standard
Sequence
SPKMVQGSGCFGRKMDRISSSSGLGCKVLRRH
Physicochemical Analysis
3466.05 Da
10.95
5.53
5.23
0.1727
-0.51
0.71
-0.21
86.78
54.69
0.0312
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1512.74
-20.75
58.0
53.0
121.0
239.0
3.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0037073 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Natriuretic peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Human serum albumin
None
Bio-Activity Profile
Vasodilator
0.0284±0.0012 μM
EC50
Mice plasma (Intravenous injection), in vivo; 40320 s
PMID15587934 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15587934/
RECORD: Rec_0071722 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Natriuretic peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Vasodilator
0.00046±0.0011 μM
EC50
Mice plasma (Intravenous injection), in vivo; 186 s
PMID15587934 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15587934/
RECORD: Rec_0075760 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Enzyme
9606
Structure & Mods
cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Approx. 18 mins
Evidence URLhttps://webs.iiitd.edu.in/raghava/thpdb2/display_thppid.php?details=Th1109
RECORD: Rec_0127012 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Natriuretic peptide
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
10-26
Bio-Activity Profile
Cardiac fibrosis Inhibitor
Human kidney membrane extract, in vitro; 480 s
PMID21459096 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21459096/
RECORD: Rec_0208004 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Natriuretic peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Natriuretic Vasodilator
in vitro; 234 s
PMID8076909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8076909/
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