Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC540H876N148O162S2

DescriptionStandard

        PDLTGHEKFGLGNVKYNISRIRVTAVELPSASISLLPGSGIKLVIGNASLTIDMNWNIRTWIFKDSGRGTVHISKVFVTAVFSTPLPDAGPTSVALSSCRTTSGDVDIKLNGKT
    

Molecular Weight12097.76 Da

Isoelectric Point (pI)9.59

Net Charge (pH 7.0)4.13

Net Charge (pH 7.4) 3.93

Charge Density (pH 7.0) 0.0362

GRAVY Index0.10

Hydrophobic Moment 0.54

Boman Index0.12

Instability Index19.06

Aliphatic Index 99.12

Aromaticity 0.0614

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4936.95

LogP -55.20

H-bond Donors 176.0

H-bond Acceptors 170.0

Rotatable Bonds 396.0

Heavy Atoms 852.0

Ring Count 17.0

Amide Bonds 119.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0041660 VERIFIED: NO

Provenance & Taxonomy

OrganismUrocynchramus pylzowi [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria