Peptide Database

Peptide NameAmphipathic peptide CT2 (StCT2) (Non-disulfide-bridged peptide 4.15) (NDBP-4.15) (Non-disulfide-bridged peptide 5.17) (NDBP-5.17)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC355H559N89O106S5

DescriptionStandard

        MKTQFAVLIISMILMQMLVQTEAGFWGKLWEGVKSAIGKRSLRNQDQFDNMFDSDLSDADLKLLDDLFD
    

Molecular Weight7930.09 Da

Isoelectric Point (pI)4.47

Net Charge (pH 7.0)-4.49

Net Charge (pH 7.4) -4.72

Charge Density (pH 7.0) -0.0650

GRAVY Index-0.01

Hydrophobic Moment 0.61

Boman Index0.08

Instability Index30.72

Aliphatic Index 97.54

Aromaticity 0.1014

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3181.14

LogP -25.01

H-bond Donors 108.0

H-bond Acceptors 107.0

Rotatable Bonds 275.0

Heavy Atoms 555.0

Ring Count 9.0

Amide Bonds 75.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0329406 VERIFIED: YES

Provenance & Taxonomy

OrganismScorpiops tibetanus [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-positive Cytolytic Non-hemolytic

TargetGram-positive bacteria