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MYP_050252
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Basic Information
Brevinin-2CE
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
22 amino acids
C119H187N25O30S2
Standard
Sequence
FTSKKSMLLFFFLGTISLSLCQ
Physicochemical Analysis
2512.04 Da
9.31
1.75
1.53
0.0795
1.04
0.26
0.37
2.26
106.36
0.1818
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
890.93
-5.60
33.0
34.0
84.0
176.0
4.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0067211 VERIFIED: YES
Provenance & Taxonomy
Chinese brown [Animal]
Brevinin
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID21303203 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21303203/
RECORD: Rec_0211589 VERIFIED: YES
Provenance & Taxonomy
Rana chensinensis [Animal]
Brevinin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-positive Anti-Gram-negative
PMID21303203 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21303203/
RECORD: Rec_0250131 VERIFIED: YES
Provenance & Taxonomy
Rana kukunoris [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0253117 VERIFIED: YES
Provenance & Taxonomy
Rana chensinensis [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperPubMed PMID: 21303203 PMID21303203 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21303203/
RECORD: Rec_0330671 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 54.5%, E 0.0%, T 13.6%, C 31.8% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Anti-Gram-positive Anti-Gram-negative
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
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