Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length438 amino acids

Chemical FormulaC2154H3410N552O627S23

DescriptionStandard

        MNQRREAVETPFNLVNHSAVIQLSGPRKMLPAVIVVLMLISFTCGENPAIQVILTSKGLQYGKHIGTGLVQEKLEHITLPDFSGKVFGIHYILTGHDGGSFNMAIFGLDVTSVVKLGKDPEGHLSVTSVSCDAQVGDVDIQFEGGASWMFQPFVEHFKGRMRGEIMSKICPNVEESIVSLEYHLQAMEVSIQVDEDLVLDIPLTGVPVIDASSMILSLKGEFYDRKTHEPPFEAQNFTVPEQPDYMLSMGLSEFTVNSASYALYSGGRLHVLITDSMIPPYIHYASTPSSMGPYVPQLPKMFPGLLMNLQVYASEVPMLSFQPGVVKLDLAGVVKASAIEPNSTQIPLFKLNVDLKFDGKVWVAAGRLKGSMALQSLTLTLAGSEVGHFETDTLESLVKMGVMAGLAKLNVELGKGVDLPRMRNAQLVNTVLGWKRDL
    

Molecular Weight47808.93 Da

Isoelectric Point (pI)5.48

Net Charge (pH 7.0)-11.42

Net Charge (pH 7.4) -12.40

Charge Density (pH 7.0) -0.0261

GRAVY Index0.14

Hydrophobic Moment 0.53

Boman Index0.17

Instability Index37.53

Aliphatic Index 99.61

Aromaticity 0.0753

Extinction Coeff. Reduced 32890.00

Extinction Coeff. Oxidized 33015.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0005115 VERIFIED: NO

Provenance & Taxonomy

OrganismDissostichus mawsoni [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria