Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC449H733N119O147S8

DescriptionStandard

        MRTLSLLLALLFLAAQTLAQPIDEGAEEVITEEPEITETQDPTTIMLIERGIDGDSTDPKRGTITCYCRLSCYLWEKSSGTCRLSNRTYKLCC
    

Molecular Weight10406.85 Da

Isoelectric Point (pI)4.59

Net Charge (pH 7.0)-5.53

Net Charge (pH 7.4) -5.87

Charge Density (pH 7.0) -0.0595

GRAVY Index-0.13

Hydrophobic Moment 0.60

Boman Index0.00

Instability Index41.61

Aliphatic Index 92.37

Aromaticity 0.0538

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4290.00

LogP -43.93

H-bond Donors 157.0

H-bond Acceptors 150.0

Rotatable Bonds 346.0

Heavy Atoms 723.0

Ring Count 10.0

Amide Bonds 96.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0271854 VERIFIED: NO

Provenance & Taxonomy

OrganismOrnithorhynchus anatinus [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal