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MYP_050180
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Basic Information
GN-14
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
9 amino acids
C69H102N22O10
Standard
Sequence
RLWKRWWIR
Physicochemical Analysis
1399.69 Da
12.00
3.76
3.55
0.4177
-1.31
0.77
-0.47
135.07
86.67
0.3333
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
555.21
0.46
23.0
14.0
43.0
101.0
6.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0006367 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
HeLa
200 μg/mL
IC50
PaperPubMed PMID: 25941221 PMID25941221 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25941221/
RECORD: Rec_0111129 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
12.5 μg/mL
MIC
PMID26662856 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26662856/
RECORD: Rec_0128695 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
25 μg/mL
MIC
PMID26662856 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26662856/
RECORD: Rec_0178019 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes: >400μg/ml
<10 %
Hemolysis
PaperPubMed PMID: 25941221 PMID25941221 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25941221/
RECORD: Rec_0269179 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 25941221 PMID25941221 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25941221/
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