Peptide Database

Peptide NameGastrin

Function Ontology

Gastrointestinal bioactivity

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length53 amino acids

Chemical FormulaC289H407N77O82S

DescriptionStandard

        DWPEPPSQEQQQRFISRFLPHVFAELSDRKGFVQGNGAVEALHDHFYPDWMDF
    

Molecular Weight6303.85 Da

Isoelectric Point (pI)4.76

Net Charge (pH 7.0)-4.96

Net Charge (pH 7.4) -5.33

Charge Density (pH 7.0) -0.0937

GRAVY Index-0.78

Hydrophobic Moment 0.79

Boman Index-0.04

Instability Index48.51

Aliphatic Index 51.51

Aromaticity 0.1698

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2537.07

LogP -20.32

H-bond Donors 83.0

H-bond Acceptors 81.0

Rotatable Bonds 196.0

Heavy Atoms 449.0

Ring Count 19.0

Amide Bonds 58.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0349256 VERIFIED: YES

Provenance & Taxonomy

OrganismGallus gallus [Animal]

FamilyGastrin/cholecystokinin

Tax ID9031

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone Gastrointestinal Neuropeptide

RECORD: Rec_0362410 VERIFIED: YES

Provenance & Taxonomy

OrganismGallus gallus [Animal]

FamilyGastrin

Tax ID9031

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

C-TermAmidation

Other Mods47:Sulfotyrosine

Bio-Activity Profile

Function

Hormone Endocrine

Half-LifeMammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour

RECORD: Rec_0369119 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/