Peptide Database

Peptide NameInterferon-induced transmembrane protein 3

Function Ontology

Antiviral

Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HCV

Antiviral ▸ Antiviral mechanism ▸ Viral budding inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Antiviral ▸ Antiviral mechanism ▸ Viral release inhibition

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length133 amino acids

Chemical FormulaC669H1037N169O183S8

DescriptionStandard

        MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTILLIVIPVLIFQAYG
    

Molecular Weight14631.93 Da

Isoelectric Point (pI)6.49

Net Charge (pH 7.0)-1.08

Net Charge (pH 7.4) -1.62

Charge Density (pH 7.0) -0.0082

GRAVY Index0.38

Hydrophobic Moment 0.47

Boman Index0.26

Instability Index44.63

Aliphatic Index 101.13

Aromaticity 0.0977

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17085.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5498.83

LogP -44.44

H-bond Donors 188.0

H-bond Acceptors 195.0

Rotatable Bonds 459.0

Heavy Atoms 1029.0

Ring Count 30.0

Amide Bonds 143.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0238816 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyIFITM

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsPhosphorylation Ser20

Bio-Activity Profile

Function

Antiviral Entry inhibitor Release inhibition Budding inhibition Interferon pathway modulator Protein degradation regulator Anti-HCV

TargetHepatitis C virus(HCV)

RECORD: Rec_0377667 VERIFIED: YES