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MYP_050100
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Basic Information
Ctry2459
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HCV
Antiviral ▸ Virucidal activity
Enzyme modulation ▸ Enzyme inhibition ▸ Infection inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
9 amino acids
C57H83N11O11
Standard
Sequence
FLGFLKNLF
Physicochemical Analysis
1098.34 Da
8.75
0.76
0.55
0.0843
1.33
0.54
0.55
-0.54
130.00
0.3333
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
365.23
0.78
12.0
12.0
35.0
79.0
3.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0220209 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Toxic Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0252576 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral
Human erythrocytes
137.9 μg/mL
HC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/23415044/ PMID23415044 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23415044/
RECORD: Rec_0257623 VERIFIED: YES
Provenance & Taxonomy
Chaerilus tryznai [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human RBC ( HC50 = 137 microg/ml ) [HC50
137 μg/mL
Hemolysis
PMID23415044 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23415044/
RECORD: Rec_0267330 VERIFIED: YES
Provenance & Taxonomy
Chaerilus tryznai [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
cells
79.8 μg/mL
CC50
PaperDesign of histidine-rich peptides with enhanced bioavailability and inhibitory activity against hepatitis C virus. Biomaterials. 2013 Feb 13;34(13):3511-3522. doi: 10.1016/j.biomaterials.2013.01.075. PMID: 23415044. PMID23415044 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23415044/
RECORD: Rec_0333666 VERIFIED: YES
Provenance & Taxonomy
Chaerilus tryznai [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
Staphylococcus aureus AB94004 or ATCC 25923 or ATCC 6538
11.38 μM
MIC
PaperDesign of histidine-rich peptides with enhanced bioavailability and inhibitory activity against hepatitis C virus.
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