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MYP_050090
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Basic Information
Defensin-like protein 1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Fungicidal activity
Enzyme modulation ▸ Enzyme inhibition ▸ Protein Translation Inhibitor
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Plant bioactivity ▸ Plant defense peptide
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
47 amino acids
C209H352N80O59S10
Standard
Sequence
RICRRRSAGFKGPCVSNKNCAQVCMQEGWGGGNCDGPLRRCKCMRRC
Physicochemical Analysis
5250.18 Da
9.77
8.68
8.36
0.1847
-0.72
0.49
-0.33
88.70
33.19
0.0426
5500.00
6000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2303.90
-31.54
91.0
78.0
178.0
358.0
5.0
51.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0002856 VERIFIED: YES
Provenance & Taxonomy
Hordeum vulgare [Plant]
DEFL family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-47; 14-34; 20-41; 24-43
Bio-Activity Profile
Antimicrobial DEFL family Antifungal Host defense
PaperPDB 1GPT structural record; NMR; chain A; residues 1-47
RECORD: Rec_0017998 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0021654 VERIFIED: YES
Provenance & Taxonomy
Hordeum vulgare [Plant]
Thionin
4513;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPrimary structure and inhibition of protein synthesis in eukaryotic cell-free system of a novel thionin, gamma-hordothionin, from barley endosperm. Eur. J. Biochem. 194:533-539 Evidence URLhttps://www.uniprot.org/uniprotkb/P20230/entry
RECORD: Rec_0095650 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperOsborn R. W., De Samblanx G. W., Thevissen K., Goderis I., Torrekens S., Van Leuven F., Attenborough S., Rees S. B., Broekaert W.. Isolation and characterisation of plant defensins from seeds of Asteraceae, Fabaceae, Hippocastenaceae and Saxifragaceae. FEBS LETT., 368, 257-262.
RECORD: Rec_0246600 VERIFIED: YES
Provenance & Taxonomy
Hordeum vulgare [Plant]
Defensin
4513
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
Bio-Activity Profile
Antimicrobial Protein Translation Inhibitor
PMID2176600;8380707 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2176600/
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