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MYP_050055
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Basic Information
B7NP(B7 without prolines)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Influenza virus
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
16 amino acids
C82H154N24O17
Standard
Sequence
RRKKVALLAVLLALLA
Physicochemical Analysis
1748.25 Da
12.00
3.76
3.55
0.2349
1.35
0.23
0.18
39.87
207.50
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
675.66
-1.88
25.0
21.0
61.0
123.0
0.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0013113 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-Influenza virus Replication inhibition
Influenza virus | MDCK cells
0.3±0.1 μM
EC50
Mammalian: 1 h; Yeast: 2 min; E. coli: 2 min
PaperIdentification of the minimal active sequence of an anti-influenza virus peptide. | Jones JC, Settles EW, Brandt CR, Schultz-Cherry S. | Antimicrob Agents Chemother. 2011 Apr;55(4):1810-3. | DOI:10.1128/AAC.01428-10 | PMID:21220525 PMID21220525 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21220525/
RECORD: Rec_0196939 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Influenza virus:inhibit hemagglutination of 64 HA units of virus of MDCK cells
0.3±0.1 μM
EC50
PaperPubMed PMID: 21220525 PMID21220525 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21220525/
RECORD: Rec_0198708 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 21220525 PMID21220525 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21220525/
RECORD: Rec_0249270 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Broad-spectrum antiviral peptide
32630.0
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antiviral Anti-Influenza
Influenza virus
0.5 ± 0.5 μM
EC50
PaperNovel Antiviral Peptides Against Influenza Virus Evidence URLhttps://patents.google.com/patent/US20100041604/en PatentUS 20100041604
RECORD: Rec_0340109 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PaperPubMed PMID: 21220525 PMID21220525 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21220525/
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