Peptide Database

Peptide NameSLAY-screened peptide P3763

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC110H162N28O30S

DescriptionStandard

        PHYSLGHSSKYTRSTIMYFL
    

Molecular Weight2388.70 Da

Isoelectric Point (pI)9.56

Net Charge (pH 7.0)2.13

Net Charge (pH 7.4) 1.96

Charge Density (pH 7.0) 0.1064

GRAVY Index-0.42

Hydrophobic Moment 0.39

Boman Index0.05

Instability Index70.67

Aliphatic Index 58.50

Aromaticity 0.2000

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 929.58

LogP -8.30

H-bond Donors 36.0

H-bond Acceptors 35.0

Rotatable Bonds 74.0

Heavy Atoms 169.0

Ring Count 7.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0161287 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/