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MYP_050034
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Basic Information
Thyroliberin
Hormonal / Endocrine ▸ Hormone peptide
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
3 amino acids
C16H24N6O5
Standard
Sequence
QHP
Physicochemical Analysis
380.40 Da
6.74
-0.15
-0.41
-0.0509
-2.77
0.33
-0.38
-2.93
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
184.50
-1.89
5.0
6.0
9.0
27.0
2.0
3.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0186454 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Thyrotropin-releasing hormone
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator
Experimental: ~20 minutes; /1200 seconds; Mammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Thyrotropin-releasing hormone (Homo sapiens): PMID 17498958 PMID17498958 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17498958/
RECORD: Rec_0193404 VERIFIED: NO
Provenance & Taxonomy
Danio rerio [Animal]
TRH
7955
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Pyroglutamate
Amidation
Bio-Activity Profile
Hormone Neuropeptide
RECORD: Rec_0230529 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Thyrotropin-releasing hormone
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Feeding regulator
the anterior pituitary gland
Experimental: ~20 minutes; /1200 seconds; Mammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Thyrotropin-releasing hormone (Rattus norvegicus): PMID 17498958 PMID17498958 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17498958/
RECORD: Rec_0300642 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
TRH
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Neuropeptide
RECORD: Rec_0304415 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
2-aminooctanoic acid
Amidation
Bio-Activity Profile
Thyroid-stimulating hormone release stimulation
LC-MS
Homogenate of Caco-2 cells, in vitro; ~1200 s
PMID17498958 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17498958/
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