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MYP_049976
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Basic Information
TB_L1FK
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C72H125N15O15
Standard
Sequence
FLPIVGLLKSLLK
Physicochemical Analysis
1440.85 Da
10.00
1.76
1.55
0.1352
1.53
0.55
0.49
-2.08
202.31
0.0769
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
476.00
0.78
16.0
17.0
48.0
102.0
2.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0145846 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
PBMCs
52 μM
IC50
PMID28443279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28443279/
RECORD: Rec_0149075 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
MS Staphylococcus aureus NCTC 6571
128 μg/mL
MIC
PMID30718667;28443279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30718667/
RECORD: Rec_0156276 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae M6
128 μg/mL
MIC
PMID30718667;28443279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30718667/
RECORD: Rec_0164496 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa NCTC 13437
128 μg/mL
MIC
PMID30718667;28443279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30718667/
RECORD: Rec_0215340 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumanii AYE
64 μg/mL
MIC
PMID30718667;28443279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30718667/
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