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MYP_049972
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Basic Information
Compound 12
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
10 amino acids
C55H99N25O12S2
Standard
Sequence
RTRCRFLRRC
Physicochemical Analysis
1366.66 Da
11.82
4.74
4.51
0.4740
-1.16
0.71
-0.99
85.54
39.00
0.1000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
654.95
-7.39
29.0
19.0
46.0
94.0
1.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0088513 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
C9
Amidation
f=D-Phe
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
Human dermal fibroblasts
164 μg/mL
IC50
PaperPubMed PMID: 26024044 PMID26024044 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26024044/
RECORD: Rec_0098060 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Cytotoxic
Madin-Darby canine kidney cells
190 μg/mL
IC50
PMID26024044 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26024044/
RECORD: Rec_0115331 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 9027
16-32 μg/mL
MIC
PMID26024044 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26024044/
RECORD: Rec_0118346 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
C9
Amidation
f=D-Phe
Bio-Activity Profile
Antimicrobial Anticancer
PC-12
225 μg/mL
IC50
PaperPubMed PMID: 26024044 PMID26024044 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26024044/
RECORD: Rec_0126829 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
C9
Amidation
f=D-Phe
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
Madin-Darby canine kidney cells
190 μg/mL
IC50
PaperPubMed PMID: 26024044 PMID26024044 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26024044/
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