Peptide Database

Peptide NameSyn-xiamencin-73

Function Ontology

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Venom / Toxin ▸ General toxin ▸ Toxicity

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC138H229N41O32

DescriptionStandard

        AGRQALKLYLKEELRKRGKKAFIAW
    

Molecular Weight2974.55 Da

Isoelectric Point (pI)10.64

Net Charge (pH 7.0)5.80

Net Charge (pH 7.4) 5.59

Charge Density (pH 7.0) 0.2318

GRAVY Index-0.67

Hydrophobic Moment 0.58

Boman Index-0.24

Instability Index34.11

Aliphatic Index 94.00

Aromaticity 0.1200

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1231.23

LogP -7.05

H-bond Donors 45.0

H-bond Acceptors 38.0

Rotatable Bonds 106.0

Heavy Atoms 211.0

Ring Count 4.0

Amide Bonds 25.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0085810 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiparasitic

TargetL. donovani

Activity3.91 μM

MethodIC50

RECORD: Rec_0321481 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiparasitic Toxicity

TargetTHP-1 cells

Activity<20 μM

MethodCC50