Peptide Database

Peptide NameSLAY-screened peptide P3807

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC66H81N15O15

DescriptionStandard

        THVVHWYGYY
    

Molecular Weight1324.44 Da

Isoelectric Point (pI)6.61

Net Charge (pH 7.0)-0.43

Net Charge (pH 7.4) -0.73

Charge Density (pH 7.0) -0.0430

GRAVY Index-0.39

Hydrophobic Moment 0.20

Boman Index0.34

Instability Index1.48

Aliphatic Index 58.00

Aromaticity 0.4000

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 9970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 479.29

LogP -0.41

H-bond Donors 18.0

H-bond Acceptors 17.0

Rotatable Bonds 34.0

Heavy Atoms 96.0

Ring Count 7.0

Amide Bonds 9.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0130682 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/