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MYP_049917
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Basic Information
Unnamed
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
35 amino acids
C172H298N44O43S
Standard
Sequence
GFGTILKALAKIAGKVVKKLATKPGATYMLKENLK
Physicochemical Analysis
3702.54 Da
10.30
6.75
6.54
0.1930
0.15
0.70
0.11
2.96
108.86
0.0571
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1413.40
-9.49
49.0
51.0
131.0
260.0
3.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0118724 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 57.1%, E 0.0%, T 22.9%, C 20.0% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Toxic Hemolytic Cytotoxic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0154747 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Toxic Cytotoxic
PaperIn silico approach for predicting toxicity of peptides and proteins PMID24058508 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24058508/
RECORD: Rec_0154923 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Cytolytic
Human erythrocytes
2.6 μM
EC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/23523532/ PMID23523532 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23523532/
RECORD: Rec_0272348 VERIFIED: NO
Provenance & Taxonomy
Cupiennius salei [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Toxin
RECORD: Rec_0414443 VERIFIED: NO
Provenance & Taxonomy
Cupiennius salei [Animal]
Cupiennin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperCupiennin-2a (Cu-2a) Evidence URLhttps://www.uniprot.org/uniprotkb/B3EWT6/entry