Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length120 amino acids

Chemical FormulaC566H924N168O165S12

DescriptionStandard

        MKLLPLACAVVGFLAPACEGGVSCGRKFLGYCRMYCHPQERTLIMCDNYRACCVKGIMPDPIISSTHQRSKNPVRKAHKETAASTAPKLSSTPRQESSPSFPSTLLNSLSQYIRGKTRAS
    

Molecular Weight13107.20 Da

Isoelectric Point (pI)9.62

Net Charge (pH 7.0)10.68

Net Charge (pH 7.4) 10.17

Charge Density (pH 7.0) 0.0890

GRAVY Index-0.26

Hydrophobic Moment 0.65

Boman Index-0.05

Instability Index60.17

Aliphatic Index 69.17

Aromaticity 0.0583

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5320.80

LogP -62.33

H-bond Donors 195.0

H-bond Acceptors 191.0

Rotatable Bonds 427.0

Heavy Atoms 911.0

Ring Count 20.0

Amide Bonds 126.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0340890 VERIFIED: NO

Provenance & Taxonomy

OrganismErinaceus europaeus [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic