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MYP_049863
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Basic Information
Turgencin B
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
35 amino acids
C143H248N42O46S8
Standard
Sequence
GIKEMLCNMACAQTVCKKSGGPLCDTCQAACKALG
Physicochemical Analysis
3548.27 Da
8.33
1.70
1.40
0.0486
0.27
0.43
0.10
36.08
67.14
0.0000
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1412.57
-18.05
53.0
56.0
121.0
239.0
1.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0284310 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human melanoma A2058
4.1 μM
IC50
PMID31940927 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31940927/
RECORD: Rec_0288017 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [Animal]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
7-31, 11-27, 16-24
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer Cytotoxic
PMID31940927 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31940927/
RECORD: Rec_0332663 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
12.5 μM
MIC
PMID31940927 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31940927/
RECORD: Rec_0333296 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [Animal]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
7-31, 11-27, 16-24
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer
Gram-positive bacteria: Corynebacterium glutamicum ATCC 13032
1.6 μM
MIC
PMID31940927 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31940927/
RECORD: Rec_0360395 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [Animal]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
7-31, 11-27, 16-24
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer
Escherichia coli ATCC 25922
12.5 μM
MIC
PMID31940927 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31940927/
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