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MYP_049862
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Basic Information
VAVR
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
15 amino acids
C85H143N31O17
Standard
Sequence
RRGWVLALVLRYGRR
Physicochemical Analysis
1871.24 Da
12.00
4.76
4.55
0.3173
-0.26
0.71
-0.31
84.77
123.33
0.1333
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
816.24
-5.09
33.0
22.0
61.0
133.0
3.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0251036 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
sheep RBCs
15 μM
Hemolysis
PMID19445503 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19445503/
RECORD: Rec_0259873 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Sheep erythrocytes
5 μM
Hemolysis
PaperRathinakumar R, Walkenhorst WF, Wimley WC. Broad-spectrum antimicrobial peptides by rational combinatorial design and high-throughput screening: the importance of interfacial activity. J Am Chem Soc. 2009 Jun 10;131(22):7609-7617. doi:10.1021/ja8093247. PMID19445503 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19445503/
RECORD: Rec_0314948 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus
PMID19445503 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19445503/
RECORD: Rec_0325222 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli
PMID19445503 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19445503/
RECORD: Rec_0337568 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
0.5 μM
Hemolysis
PaperRathinakumar R, Walkenhorst WF, Wimley WC. Broad-spectrum antimicrobial peptides by rational combinatorial design and high-throughput screening: the importance of interfacial activity. J Am Chem Soc. 2009 Jun 10;131(22):7609-7617. doi:10.1021/ja8093247. PMID19445503 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19445503/
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