Peptide Database

Peptide NameHepcidin

Function Ontology

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Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC85H146N26O25S8

DescriptionStandard

        ICIFCCSCCRNSKCGICCKT
    

Molecular Weight2188.75 Da

Isoelectric Point (pI)8.53

Net Charge (pH 7.0)2.68

Net Charge (pH 7.4) 2.36

Charge Density (pH 7.0) 0.1339

GRAVY Index0.89

Hydrophobic Moment 0.37

Boman Index0.07

Instability Index27.73

Aliphatic Index 58.50

Aromaticity 0.0500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 833.94

LogP -11.18

H-bond Donors 38.0

H-bond Acceptors 36.0

Rotatable Bonds 72.0

Heavy Atoms 144.0

Ring Count 1.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0371149 VERIFIED: YES

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

FamilyHepcidin

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)