Peptide Database

Peptide NameAntimicrobial peptide AmAMP1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length117 amino acids

Chemical FormulaC567H925N171O177S13

DescriptionStandard

        MPSIRVLFVLLAVILLFMEVKMTSAASIVKDVDEDETLENEDGEAMENSWPWHGVEDTSDYSDLSDLANSEKRGTCIDLGSRLYCKLIRRRGMCRSRSHRARIAMMRCERSCGRCHL
    

Molecular Weight13386.29 Da

Isoelectric Point (pI)5.91

Net Charge (pH 7.0)-2.27

Net Charge (pH 7.4) -2.75

Charge Density (pH 7.0) -0.0194

GRAVY Index-0.30

Hydrophobic Moment 0.81

Boman Index-0.12

Instability Index51.46

Aliphatic Index 83.33

Aromaticity 0.0513

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5649.85

LogP -58.51

H-bond Donors 210.0

H-bond Acceptors 191.0

Rotatable Bonds 457.0

Heavy Atoms 928.0

Ring Count 13.0

Amide Bonds 119.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0079900 VERIFIED: NO

Provenance & Taxonomy

OrganismAcropora millepora [Animal]

FamilyCoral AMP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetAcinetobacter spec., B.algicola, Bacillus megaterium, Coral, Escherichia coli, Staphylococcus aureus

MethodQualitative functional evidence