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MYP_049801
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Basic Information
Human ApoE apolipoprotein derived peptide ApoEdpL-W
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Enzyme modulation ▸ Enzyme inhibition ▸ Binding inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
18 amino acids
C148H202N48O19
Standard
Sequence
WRKWRKRWWWRKWRKRWW
Physicochemical Analysis
2957.50 Da
12.00
9.76
9.55
0.5420
-2.77
0.58
-0.82
109.31
0.00
0.4444
44000.00
44000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1159.82
0.53
49.0
29.0
91.0
215.0
16.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0007759 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Antifungal
Candida glabrata[MIC90 >20 microM]
PMID21807970 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21807970/
RECORD: Rec_0046315 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Antifungal
Candida tropicalis[MIC90 = 5 microM]
PMID21807970 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21807970/
RECORD: Rec_0048775 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Hemolytic
human red blood cells at 35 μM
PaperPubMed PMID: 17681018 PMID17681018 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17681018/
RECORD: Rec_0068280 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Antifungal
HSV-1
PMID21807970 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21807970/
RECORD: Rec_0085652 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Antifungal
Candida parapsilosis[MIC90 = 20 microM]
PMID21807970 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21807970/
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