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MYP_049777
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Basic Information
Lynronne-1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
19 amino acids
C113H182N34O24
Standard
Sequence
LPRRNRWSKIWKKVVTVFS
Physicochemical Analysis
2400.87 Da
12.00
5.76
5.55
0.3030
-0.56
0.76
-0.25
69.03
86.84
0.1579
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
977.45
-6.20
37.0
30.0
78.0
171.0
6.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0014671 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Acinetobacter baumannii and 14 clinical strains
4-16 μg/mL
MIC
PaperThe rumen microbiome: an underexplored resource for novel antimicrobial discovery PMID29214045 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29214045/
RECORD: Rec_0057847 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
8-32 μg/mL
MIC
PaperThe rumen microbiome: an underexplored resource for novel antimicrobial discovery PMID29214045 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29214045/
RECORD: Rec_0065047 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes
20 %
Hemolysis
PaperPubMed PMID: 29214045 PMID29214045 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29214045/
RECORD: Rec_0076997 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Toxicity
it showed poor cytotoxicity to multiple cell lines
>184 μg/mL
CC50
PaperThe rumen microbiome: an underexplored resource for novel antimicrobial discovery PMID29214045 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29214045/
RECORD: Rec_0083654 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 29213
256-64 μg/mL
MIC
PMID34028161 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34028161/
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