Peptide Database

Peptide NameNisin Z

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length57 amino acids

Chemical FormulaC248H418N70O80S7

DescriptionStandard

        MSTKDFNLQLVSVSKKDSGASPPITSISLCTPGCKTGALMGANMKTATCHCSIHVSK
    

Molecular Weight5884.85 Da

Isoelectric Point (pI)9.13

Net Charge (pH 7.0)3.63

Net Charge (pH 7.4) 3.25

Charge Density (pH 7.0) 0.0637

GRAVY Index0.03

Hydrophobic Moment 0.29

Boman Index0.08

Instability Index44.04

Aliphatic Index 70.18

Aromaticity 0.0175

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2387.35

LogP -32.93

H-bond Donors 87.0

H-bond Acceptors 93.0

Rotatable Bonds 196.0

Heavy Atoms 405.0

Ring Count 6.0

Amide Bonds 59.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0085939 VERIFIED: NO

Provenance & Taxonomy

OrganismLactococcus lactis subsp. lactis [Bacterium]

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0140110 VERIFIED: NO

Provenance & Taxonomy

OrganismLactococcus lactis subsp. lactis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence