Peptide Database

Peptide NameProtegrin 2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC79H130N28O18S4

DescriptionStandard

        RGGRLCYCRPRFCVCV
    

Molecular Weight1888.31 Da

Isoelectric Point (pI)9.37

Net Charge (pH 7.0)3.72

Net Charge (pH 7.4) 3.46

Charge Density (pH 7.0) 0.2325

GRAVY Index0.21

Hydrophobic Moment 0.50

Boman Index-0.20

Instability Index9.68

Aliphatic Index 60.62

Aromaticity 0.1250

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 758.86

LogP -7.24

H-bond Donors 33.0

H-bond Acceptors 26.0

Rotatable Bonds 58.0

Heavy Atoms 129.0

Ring Count 3.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0185776 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyProtegrin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)