Peptide Database

Peptide NameS-type Pyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length460 amino acids

Chemical FormulaC2209H3459N617O698S10

DescriptionStandard

        MSHGQEKAGMTQILGTGEGKTSSAAKEPVVERKPAQVFFESMALAASMSGYYAGPTATTLGNSLSLGAGTAAGVGEGVAGARVLAAPNPLTVALLAIFYSPSLNEGETETLQNIRGDQLYQNLIHGQMMVGAFTRVNSTVIQGDYVPEYELREIARQNGTVRTRVRFRIEEDPESGELVSRSYEVGEKSGLDRVRVRFAKQLDKETWGFEDPSIKGTFVWSRSAGQGRFEWGASQTTVHDGSAGGSTTPPTPIPEPRSVWGLPNPAPASLPPVPGTPIPEEQGPNIETLPIEDRDFNDFIIVDPMGGVPAIYVYFQKASVRDLEVDYYGNFEGRSRQGLYEVDHIPSKEAVRIYLKGTYPNLKDDIIEQMTDRVAAVAIPIEVHRQCSETYGGKNNSKFRTQDGGLVTQKVLDASNLEAAVDANWDANAECLRNEYGVSDEKIEEIRAKLHELNRKAGLY
    

Molecular Weight50148.46 Da

Isoelectric Point (pI)5.02

Net Charge (pH 7.0)-15.89

Net Charge (pH 7.4) -16.58

Charge Density (pH 7.0) -0.0346

GRAVY Index-0.44

Hydrophobic Moment 0.64

Boman Index-0.01

Instability Index40.10

Aliphatic Index 76.54

Aromaticity 0.0783

Extinction Coeff. Reduced 52830.00

Extinction Coeff. Oxidized 52955.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0081130 VERIFIED: YES

Provenance & Taxonomy

OrganismKlebsiella pneumoniae 909957 [Bacterium]

FamilyPyocin/Colicin

Tax ID1269006

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli