Peptide Database

Peptide NameColicin E3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length302 amino acids

Chemical FormulaC1494H2284N416O456S4

DescriptionStandard

        MGATSLAATAGITATAGTAGETLLTALEYLGGGLKTAGRWLAPHPGTLFVFGMFYSPKLNSGEQDFIDRMRLEQAAKTQGDAETRVRFRWEPDKYGVLTPKGYHVGAEGGLGKVPVRMLHKNAATENYEFYEDGTDSPTLVWTPDNPVFTAPPHTGNQDDVYIPSNILVHPEDEIQGITSTETPTSDERTFRDYILVHPDGIFDPIYIYLNNDHKYHVSPKGHTPLPAFPDAKRAPRKTPIQGSSGQLRARWKDSEGRIYEWDSQHGTVEIYDRSGRRHIGEFDPTTGKQTKPADPSRKVEK
    

Molecular Weight33496.89 Da

Isoelectric Point (pI)6.00

Net Charge (pH 7.0)-5.49

Net Charge (pH 7.4) -6.35

Charge Density (pH 7.0) -0.0182

GRAVY Index-0.70

Hydrophobic Moment 0.70

Boman Index-0.05

Instability Index45.14

Aliphatic Index 63.34

Aromaticity 0.0960

Extinction Coeff. Reduced 46870.00

Extinction Coeff. Oxidized 46870.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0127211 VERIFIED: NO

Provenance & Taxonomy

OrganismBrenneria goodwinii [Bacterium]

FamilyColicin/Bacteriocin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence