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MYP_049646
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Basic Information
Temporin-ALd (Amolopin-2e)
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
64 amino acids
C324H535N89O94S3
Standard
Sequence
MFTMKKSLLLLFFLGTIHLSLCEQERNAEEERRDDLGERQAEVEKRFLPIAGKLLSGLSGLLGK
Physicochemical Analysis
7277.45 Da
6.57
-0.40
-0.71
-0.0063
-0.16
0.64
-0.03
43.48
106.72
0.0625
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2979.76
-23.97
105.0
98.0
258.0
510.0
6.0
66.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000255 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Hemolytic
B. pumilus (Gram-positive)
PMID19843479 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19843479/
RECORD: Rec_0127405 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperFive novel antimicrobial peptides from skin secretions of the frog, Amolops loloensis. Comp Biochem Physiol B Biochem Mol Biol. 2010 Jan;155(1):72-76. doi: 10.1016/j.cbpb.2009.10.003. PMID: 19843479. PMID19843479 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19843479/
RECORD: Rec_0139107 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Hemolytic
Escherichia coli (Gram-negative)
PMID19843479 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19843479/
RECORD: Rec_0177280 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Hemolytic
Candida albicans
PMID19843479 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19843479/
RECORD: Rec_0195065 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Hemolytic
Pseudomonas aeruginosa (Gram-negative)
PMID19843479 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19843479/
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