Peptide Database

Peptide NameAngiotensin I converting enzyme inhibitior 4

Function Ontology

Enzyme modulation ▸ Enzyme inhibition

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Standard StatusStandard

Sequence Length6 amino acids

Chemical FormulaC31H43N9O9

DescriptionStandard

        STHGVW
    

Molecular Weight685.73 Da

Isoelectric Point (pI)6.46

Net Charge (pH 7.0)-0.45

Net Charge (pH 7.4) -0.71

Charge Density (pH 7.0) -0.0755

GRAVY Index-0.30

Hydrophobic Moment 0.18

Boman Index0.29

Instability Index-8.95

Aliphatic Index 48.33

Aromaticity 0.1667

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 293.75

LogP -2.83

H-bond Donors 11.0

H-bond Acceptors 10.0

Rotatable Bonds 18.0

Heavy Atoms 49.0

Ring Count 3.0

Amide Bonds 5.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0065574 VERIFIED: YES

Provenance & Taxonomy

OrganismSepia officinalis [Animal]

FamilyAngiotensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory

TargetAngiotensin-I converting enzyme

Activity19.30 μM

MethodIC50