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MYP_049625
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Basic Information
Magainin 2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
27 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
GIGAVLKVLTTGLPALISWIKRKRQQX
Physicochemical Analysis
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0054017 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Magainin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 27
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis ATCC 6633
3.1 μM
MIC
PMID31117348 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31117348/
RECORD: Rec_0062217 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Magainin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 27
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 6538
50 μM
MIC
PMID31117348 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31117348/
RECORD: Rec_0184659 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Magainin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 27
Bio-Activity Profile
Hemolytic
Human erythrocytes [≤5% hemolysis at >250 microM]
250 μM
Hemolysis
PMID31117348 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31117348/
RECORD: Rec_0247541 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Magainin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 27
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
50 μM
MIC
PMID31117348 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31117348/
RECORD: Rec_0332001 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Magainin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 27
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae NCTC 5055
12 μM
MIC
PMID31117348 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31117348/
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