Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length58 amino acids

Chemical FormulaC263H435N71O86S7

DescriptionStandard

        MMNATENQIFVETVSDQELEMLIGGAGRGWIKTLTKDCPNVISSICAGTIITACKNCA
    

Molecular Weight6192.15 Da

Isoelectric Point (pI)4.66

Net Charge (pH 7.0)-2.53

Net Charge (pH 7.4) -2.82

Charge Density (pH 7.0) -0.0436

GRAVY Index0.24

Hydrophobic Moment 0.64

Boman Index0.16

Instability Index26.79

Aliphatic Index 90.86

Aromaticity 0.0345

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2533.39

LogP -28.48

H-bond Donors 90.0

H-bond Acceptors 91.0

Rotatable Bonds 209.0

Heavy Atoms 427.0

Ring Count 4.0

Amide Bonds 63.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0111493 VERIFIED: NO

Provenance & Taxonomy

OrganismEnterococcus columbae [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence

RECORD: Rec_0251406 VERIFIED: NO