Peptide Database

Peptide NameLysozyme (EC 3.2.1.17)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length4673 amino acids

Chemical FormulaC22222H35310N6600O7012S66

DescriptionStandard

        MAPVGFEKTSVPELYEKDSYGHSVQLDGNLVVTETDPENNRIEVSQGRLRQPTAYYRPQRAVALREEQRRRTISVEGINNFEKLEEGSVLSSLKGQVRQNRYDNPAVELQSLRNTGQNAFRQSELPAQSDNLRVATFNLESYGVRGRSDAKTPSKTDKLASAVEKANPDILAVQEVANRFGEQSPMSRITDAISSQGNGSYDYVKPPSGDRLGNQPIAVGIAYKPSEVSPVGEAETIEGEAFRGLSRKPLVQKFKDNESGETFTVINVHLKSKRGSGKYPSNIQGGFNYERLQAIGSVIDRIKESGGNAVVLGDFNAYRKEDPLVALESSGMLNISELLGERPNTYTFRGKAGSLDHVFTNPELAKTTDDVGAIASGGSDHKLLWTDFSLGESSFGRRLQTMLNQWSNRQDAVSELYREAQHPTVDIVRSTRATPKYKRSQVDESLELVRPPSELPSAFYDQFRSAETLPKVQIFQNEALNEDLNRMPFRERINRLLLQNSPIPLRDPVIKSDETFLEGGFATVGHLIDRAMGHHYHQQQKRQAQGYYTATLYQATKRLYDPKETKQGPFESLLGGIAQTVSSVSAAFLSYGLFRGTSLLSAHMEDELNRQFQQGTGQYRTGYQGRYQSVQGAREATDQTMRFVRQAYIGSEGLEGYRSLRATQLPSKAALAKYQGYFRKFQSFLMDTVLGGILETISADREQSRTAVREISEEIGKVPTIVDEGQGGIRISNIGSGRMQSLAQRWENISRQVPANLLQWFPAMRQSPQVDLTREASMSDLVGQNLQDMLSTYEQVFKMLGSFVANPRQWTREISTIYQRSGQIEREERQLIQDVAQSSQTAQTADNSVRNAGRDPSEVVEMASRRARLNERINYYESYVQPPNSKGPDIRGQSQKELFGIPIRKARRGMLGVSAVFGADYLTSFAIAGDGGLSLINYLLNPEARKARRAETDLPPVVTASAGVGGALLAGWTFPQFKTRGDIELDFQLPERDSNAVDALRQREYGPNQIDNDQLQDELRKERTFLRTQLNMSERRYQSHGEHALPKDQRRQFQGRVQGIDTYLGATPQEQQGYRTLAESFDPRQAPSQASYSRVARFNKVSAAIGFAVATTGARLTSAAVATGINLFHDSGYPTEDMSYLGAQRIDTKLPDRPLSRDEKANYIAARDYKSSLLKRSESQYRNEFTLTPQFTTPLFQLSWVERTDPSSGTKNYTFGFQLFPLLGGGITPELPVAFRLFGRPESRRKDIDSKEEWAESVAYRAATFPSELLTGVSDSGFEKLAMSVGAYGVAGAIANRVTPRGVKTSLPGRGVRTVSRGLIDFGSSVMATPAMMLDSAKVGFERVLHESAKNARDGQPVLHRAQQAITNRVFKAGRDVNRNRSARWRGIAPYALAYTASLAYIDRQMGSTAPGYSGTYVREEANKWDRTGAALGLAAAYGGVMSGGSYGYNPFAESEMVARDAYQRRLETGENAERGFKRTIKGTQPDQPIGASSGRRPTGADYNARFIGKAQTLATRAYGLYLTGQLVGKGLEAMGFKEPLFGDRETGFFRGLIVGTAQVLTGGYEQPEHPAGGNPLPKVSPQSDVKQMLAEAGYFEQGLLSETINLLNPLSFLSDSGAYADDPNVFFNFFATGQSVRDDISTSGYTQFQGSNVDLSMTTRSLSTRGLEDAEKEALKRIIAGAGEGKVSPQELVNTLRSLSPRPSRMDYTATKSSELAQTSSFAMSQALAVREFYAQNLSRKRPSTLALEHSLYLNRAGLGKTKDARLDSKALFSRFFSNFDYRSLTIGGETIPFDTGNFAQELKQSLIDNRRSGYYTQVEGIFQSLSQWAMTVGGASGATKFIPGSEFLHSDESQEAVNLQSNAFDFAKIGFGALTLGAVGYAGAMTVGRFAATLASVQERNLAEGVQRQIETIAQRVESINVNNLQQVKYHFDTNRSQGSVFIQHREDELRRIPGLSNQSPVGDYGRHVAERFEALYKGRLIPTLAQEIRGAAFTGSEAADLGKPYMSQVREIFESYDKGAISSDEMSRQIRGVLDSGEGYEQRVSRRISEILEETIDISSTQSVKLFTALTGLSGREATRDQVYDWVKSIFRHSDAGGDFTAQIQQTLEQASKEGVTPEMAMQRVKLDIASRLDRTAQLIPSDKPEPGPVEDFDEARAVGERARQVRYRRQQAMTPEPKAELGARDIPRAIGGAVDLFGKASMIQEGYGVIEGASLYADATASGDPIQARQSSKLFWGEAGILGMQSFLVKGFSGRMGLGTAGLIAAGTTAAYSSLSQHSEALQTAESKAYNFFSENLSAIPKAIGTGVNWFAEALNVLPGVEDFNLFKDVTGPLIRRGARALRQTDNQFLSLLGGVVLPRSTVLRTGMQSERKQTAYGYQRHFYGSVEAEWQRIARRRRRRSSQYGRPVDVIHSGLYGQKTTKLGKARKAVRYGGGKRVLDEFSFRANYQISQTLQLALERRQRRSDLYAQGYVYRMNEVDKTSWRSPVASSIAARAQSISAARDRGLFFVSALQDIKAGIGKSVVRPLLQEADNSYRKASYRGVVYYNTRYREKAIQDIKNLGGTLDIQPSRVGPVKAPQADWGSDVTKEVPKRIRQILRNASSVRDVVPTTAAIVKGALRDKTQRARRNARSWGANQFDGIATPPIFAKIGRAFGKRAPILRRSPQAGLYQLRKANFIQARQGNLPPLVGGLQDPEFLQAAFSDSRVRQGRATSRLFGSGLRGLLSAGVFLTRLGAETISKGLGGLGRSVPGATLRAGAYAFFSSLNLGGRLAAMGVTIAGGMVSNPLVGEIGAGILSAVDLATTGGSITSTAAGAYSLFQGSRLAFPNPKTGFRNAMGSLEQTLRVVAGQASMLPPLSVRQAISRRMPGGRAVSPNEIPVSAEDATRYRKGLFKSVKDRYSRSLPISPEFPYSQTSNVSALYGEVISPNNTFSAQPIDGQDTRSFSDSLGDLLKQGRDFIDRSRTAQYKGPPQAEGKLGQIGRAVSHRASQTSSAISQVGRRVPGVMRSLAPDVASFALDAYFINRSYRKIEDLQKGRDYQARYEQAYAEYYGNIGSTISGVGALAIASAPFTGGLSLLPALGISIVGGIAGGIVGAEYGKQRGADVYHGEDRQGQEWWAGTIAKSVAAVPILSTAYKLFRDRNRQGTQSDHSQAGDEGSSGSRRSPSPEPPGLSSGGTADATRRSLPTARQAEQRAVDRMRQQEADRLSRSSSGKAQRRVASPVEASVDKSPEKPKSANDSKIQATESESAFAEDSRRSATSTRSDDANIASDKSQFSAPTESSDTSITTDSGQSGFRGDRPAGSKNSIGSNQTRLSLSSGSNVPRGMLEELVKNQIASRRRDLSDSNISATPEPKPPRTGASDSSISADPRPTSFPQPRGPAKRSASVDDSRITSRVSNNQTESLTVTEWISPSKYKYGPKGDIELAGFETFNDMPYKGVPEANDVISKLLRESVGYGNLRSRFNAPNQEPLAFAKQFQNGGFLAIGENMRDNKGKAISMFRYFYAKGPNAVESIYNQLKSEGRLSLGDPIQNQGGEFEAFGSTIEAESPGPRYQSSEVGLDEAIRQAKGNASGGEFSFTFNLAEHGFQAPNVDQFLGSNTMYFVPEIVQENAGRYRPGLENGNQGSSRRKRGGRRLNAMFSPFPDWVDDIGSDDSILNKAGRMLSRGGQNVAKRARAQGKQVMQKGRKAIGNIGMPGVMKGLNALGTVGDIAELGFAAYGAYEVQQGVQEQNRKRAVKGGATIGGAVGGFAAGGIATAIAVGVAIALALPALAIGGLALGAGLAVGAIGSYFGSKFGGEAAGSYYDRQMAHEDVASIRQRQDQSRPSIREFAESVTASFTEGFSLAVGGGVEADRQIASEGGFFSTLGGMIGNVWQATKAAAQATVSGVSKVADLVSSTVSAGVGSTSKAGRRLGKTIKQTGQAIENWVNPSVTGERPTGREAKVSSLNEPFYQQQLNEAGVDATVTSGYGRRADPMTGRPEQHEGLDVVAPKGSKFYNPYERGRVQVADRVSGYGNAVYVKQLNEKGKPTGRRIMAGHLRSINVERGQTVSGGKALGVQGSTGHSTGDHFHIEVQKRQDGQWQDVAPSDREIIASLSGKKVVSTGSVEGKGRIDLGEDPDVSKKGLSTLKNFEGLRLNSYQDSAGVWTVGYGHTDTAKPGMSISRSRAKELLKRDLQRFEEAVAKKVDVPLSQSQFDALVSFTYNVGIGALSRSTLLEKLNRGNYEGAQKEFKKWTHAGGRELEGLVKRRKAEARLFGSEPPKEAQASDRQSSDRQVSADKGQVVFVVGHSSDRDTGAVNPATGKREEDVTPDLVKEINRLADEYGYGSAVRIASGNEKNVGESKVDKQTSSGKSFTSAAAYERQGIEYYGLHFNAVGNEEQGGRRPGIITGTERTQADRNLGSLFSMFPKNTSDFYVTRNEGSIIELGAADSPLVNTLAGAKGEESKRKAQRQVALRILRRTLKGKGYDVSNLPEPKKTEQPFQAYLKSPEKSSIDASKVEFSDSQELSKTIEAQEANQDKQLQFDSADVAIAPDPEGNRKNKATEEQNKQVEEEIKKEEEKAKLQIELAQASPDIPHSVEPAYSQVLDQWLEGPIASTDTESRNYRKAGNTKVTKKDNGNKEVNVEVEESQEAVELATASADEFSFTEGNSPVEQMVARS
    

Molecular Weight509240.38 Da

Isoelectric Point (pI)9.40

Net Charge (pH 7.0)79.70

Net Charge (pH 7.4) 76.25

Charge Density (pH 7.0) 0.0171

GRAVY Index-0.55

Hydrophobic Moment 0.99

Boman Index-0.09

Instability Index44.80

Aliphatic Index 71.93

Aromaticity 0.0775

Extinction Coeff. Reduced 380480.00

Extinction Coeff. Oxidized 380480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0087873 VERIFIED: NO

Provenance & Taxonomy

OrganismCyanobacteria bacterium SW_9_44_58 [Bacterium]

FamilyLysozyme

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic

MethodQualitative functional evidence