Peptide Database

Peptide NameMela 5

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC137H210N34O42S6

DescriptionStandard

        GSAIACGESCFKFKCYTPGCSCSYPICKKD
    

Molecular Weight3197.73 Da

Isoelectric Point (pI)8.31

Net Charge (pH 7.0)1.70

Net Charge (pH 7.4) 1.40

Charge Density (pH 7.0) 0.0567

GRAVY Index-0.01

Hydrophobic Moment 0.33

Boman Index0.06

Instability Index41.22

Aliphatic Index 32.67

Aromaticity 0.1333

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1209.93

LogP -14.34

H-bond Donors 48.0

H-bond Acceptors 50.0

Rotatable Bonds 101.0

Heavy Atoms 219.0

Ring Count 6.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0194796 VERIFIED: YES

Provenance & Taxonomy

OrganismMelicytus latifolius [Plant]

FamilyCyclotide

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Bio-Activity Profile

Function

Anticancer Cytotoxic

RECORD: Rec_0323242 VERIFIED: NO