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MYP_049550
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Basic Information
Desotamide B [V2I]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
6 amino acids
C35H54N8O8
Standard
Sequence
NILLWG
Physicochemical Analysis
714.85 Da
5.53
-0.24
-0.44
-0.0400
1.22
0.26
0.67
135.85
195.00
0.1667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
267.70
0.19
9.0
8.0
21.0
51.0
2.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0287141 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial
Human breast adenocarcinoma MCF-7
158 μM
IC50
PMID29431987;29125222 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29431987/
RECORD: Rec_0337785 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
128 μg/mL
MIC
PMID29431987;29125222 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29431987/
RECORD: Rec_0352372 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
l=D-Leu
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 29125222 PMID29125222 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29125222/
RECORD: Rec_0354130 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial
Clostridioides difficile R20291
64 μg/mL
MIC
PMID29431987;29125222 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29431987/
RECORD: Rec_0383935 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Hemolytic
Vero cells (IC50 at 90.8 microg/ml
50 μg/mL
Hemolysis
PMID29431987;29125222 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29431987/
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