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MYP_049550
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Basic Information
Desotamide B [V2I]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
6 amino acids
C35H54N8O8
Standard
Sequence
NILLWG
Physicochemical Analysis
714.85 Da
5.53
-0.24
-0.44
-0.0400
1.22
0.26
0.67
135.85
195.00
0.1667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
267.70
0.19
9.0
8.0
21.0
51.0
2.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0002752 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus epidermidis ATCC 14990
25 μg/mL
MIC
PMID29431987;29125222 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29431987/
RECORD: Rec_0040398 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecalis ATCC 33186
12.5 μg/mL
MIC
PMID29431987;29125222 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29431987/
RECORD: Rec_0067945 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial
Human hepatocellular carcinoma HepG2
606.8 μM
IC50
PMID29431987;29125222 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29431987/
RECORD: Rec_0089745 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 29213
12.5 μg/mL
MIC
PMID29431987;29125222 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29431987/
RECORD: Rec_0114003 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
l=D-Leu
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
Vero cells
90
IC50
PaperPubMed PMID: 29125222 PMID29125222 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29125222/
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